In addition to drug discovery and development, CRISPR technology has a diverse range of applications. These include the use of CRISPR technology in agriculture, synthetic biology, production of biopesticides, development of animal models, cell lines and tissue culture, gene synthesis, antibody production, development of biosensors, bioinformatics, biofuels, etc. There are a large number of companies that are focussed on exploring these applications. Some of them are:
- Agragene: This biotech company is based in San Diego, California. It is focussed on developing environmental-friendly, cost-effective biological pest control agents. This not only eliminates pests and insects but also reduces the use of harmful chemicals that helps to increase the population of beneficial insects like bees and ladybugs.
- Arcadia Biosciences: This is an agro-based American biotech company with headquarter in Davis, California. They employ CRISPR/Cas technology to improve the nutritional content of crops such as wheat, hemp, safflower oil, soybeans, etc. to meet the global demand for a healthier diet.
- Biocytogen: This biotech company is based in Massachusetts, United States. The company offers a wide range of services to the global biomedical community. Their services include gene editing in different models such as mouse, rat, and cell using different strategies of gene knock-in and knock-out; development of various animal and cell models; antibody discovery, preparation, and characterisation; and, preclinical services for drug development.
- Addgene: It is a plasmid repository located in Massachusetts, United States. This non-profit repository aims to accelerate scientific advancements through the sharing of plasmids, viral preparations, and their cloning data among laboratories across the world.
- Cardea Bio: This biotech company is based in San Diego, United States. The company focuses on the integration of biomolecular control signal networks such as DNA, RNA, proteins, etc., and the electronics realm to create the next generation of biosensors.
- CasZyme: This biotech company is based in Vilnius, Lithuania, and focuses on the use of Cas proteins for the development and characterisation of CRISPR-based molecular tools for diverse applications. In addition, the company provides various CRISPR-based research services to the larger biomedical community.
- eGenesis: This company is located in Cambridge, United States. The company uses the CRISPR technology platform to facilitate safe and effective xenotransplantation of transplantable organs, tissues, and cells, especially in humans.
- Rice Tec: This American agro-based biotech company is located in Alvin, United States, and is involved in the sustainable production of high-quality rice seeds with excellent germination rates and insecticide seed treatments. Using advanced seed technologies, Rice Tec aims to have a positive impact on the farmers, employees, and all stakeholders involved.
- Synthego: This company is located in Redwood City, United States, and offers CRISPR/Cas9 genome editing tools and services to the global biomedical community for scientific research, drug discovery and development, and production of clinical-grade biomolecules.
Other non-pharmaceutical companies using CRISPR/Cas platform include Plantedit, Pairwise, Oxford Genetics, The ODIN, transOMIC technologies, Yield10 Bioscience, etc.