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1. The enzymatic action of Cas9 nuclease can be compared to which of the following?
2. What is sgRNA and why is it called so?
3. Which of the following protein have not been used in genome editing?
4. The CRISPR sequences obtained from attacking phages are recognized by
5. Potentially, the germline gene therapy could be used to correct a genetic defect in?
6. CRISPR/Cas9 belongs to which of the following systems?
7. Which of the correct sequence of processes involved in CRISPR-mediated immunity in prokaryotes?
8. Which of the following statements is incorrect?
9. What is the classical theory of carcinogenesis?
10. What are pluripotent stem cells?
11. Which of the following statements related to DNR repair pathways is incorrect?
12. What is the application of gene knock-in and knock-out studies?
13. Which of the following is an endogenous factor leading to DNA damage?
14. Which of the following statements related to the role of PAM in CRISPR-mediated genome editing is incorrect?
15. What is the function of the Nuc lobe of Cpf1?
16. Which of the following statements related to the reverse transcriptase of HIV-1 incorrect?
17. Which of the viral vectors have a low risk of insertional mutagenesis?
18. What are the adverse effects of off-target gene editing leading to ethical concerns?
19. Which of the following leads to increased biofuel and oxygen stress tolerance?
20. Applications of CRISPR/Cas9 in mammalian cells include